Off-label Pearl: Chondrodermatitis nodularis helicis
By Ted Rosen, MD, FAAD, Editor-in-Chief Chondrodermatitis nodularis helicis is a painful degenerative condition affecting the ear. Surgical removal or intralesional steroid injections are standard therapeutic interventions. A small clinical trial involved the use of topical nitroglycerin patches, assuming that part of the pathogenesis includes localized ischemia. Self-adhesive nitroglycerin patches (at the concentration of 5mg/24 […]
Novel topical terbinafine demonstrates efficacy and safety in pivotal trial
With Amir Tavakkol, PhD “There have been numerous efforts to develop a topical formulation of terbinafine but most, if not all, have been unsuccessful because of failure to achieve adequate drug delivery to the subungual tissue. Efficacy and safety results from the phase 3 trials investigating MOB-015, topical terbinafine 10% solution, show that it has […]