Validated: A New PROM to Assess Disease Control in Chronic Prurigo

Chronic prurigo (CPG), including prurigo nodularis, is difficult to treat and dramatically affects quality of life.  So, how can dermatologists best assess whether a treatment working or not? Enter the Prurigo Control Test, which has passed muster and may be the first patient-reported outcome measure (PROM) to determine disease control and guide treatment decisions in […]

DermaSensor Empowers Internists to Diagnose Skin Cancer: What Will This Mean for Derms and Patients?

The U.S Food and Drug Administration (FDA) has cleared DermaSensor for skin cancer detection in primary care, the Company reports. Wireless and handheld, DermaSensor’s AI-powered spectroscopy technology non-invasively evaluates cellular and subcellular characteristics of a lesion, providing an immediate and objective result using an FDA-cleared algorithm.  The FDA pivotal study of more than 1,000 patients, showed […]

Practice-Changing Melanoma Research From ECOG-ACRIN Receives the 2023 Paper of the Year Distinction from the Journal of Clinical Oncology

And the 2023 Paper of the Year distinction by the Journal of Clinical Oncology goes to … a team of melanoma researchers with the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN).  The recognition is for the results of the DREAMseq randomized phase 3 clinical trial. DREAMseq (EA6134) showed an optimal treatment sequence for combination therapy in patients with advanced melanoma with […]

Label Update: FDA Green Lights Dupilumab for AD Patients With Moderate-to-Severe Hand and Foot Involvement

The U.S. Food and Drug Administration (FDA) has updated the label for dupilumab (Dupixent, Regeneron Pharmaceuticals, Inc. and Sanofi), adding efficacy and safety data for people aged 12 years and older with atopic dermatitis (AD) and uncontrolled moderate-to-severe hand and/or foot involvement.  More than twice as many atopic dermatitis patients with uncontrolled moderate-to-severe hand and/or foot […]

Exploring Microbiome Changes in Lichen Striatus Hypopigmentation: New Insights May Mean New Treatment Options

Cutibacterium acnes significantly influences the bacterial community in hypopigmented Lichen striatus (LS), new research shows. For the study, researchers from Korea led by Associate Professor Yun Hak Kim from the Department of Anatomy and the Department of Biomedical Informatics and Professor Hyun-Chang Go from the Department of Dermatology, both at Pusan National University, analyzed skin samples of […]

TDD’s Guide to Maui Derm 2024; Stay Tuned for Daily Coverage

It’s almost Maui Derm time. Led by George Martin, MD, a dermatologist in Kihei, Maui Derm is considered a top-tier event in dermatology. Hundreds of leading dermatologists, residents, and industry insiders are heading to the island for an exciting meeting packed with practice-changing lectures, panel discussions, workshops, and late-breaking research on a wide array of […]

Researchers Unravel the Molecular Basis of Pigmentation Variation Among African Populations

Researchers from the University of Pennsylvania have discovered key insights into the molecular basis of skin color variations among African populations.  Their findings, published in Nature Genetics, broaden the understanding of human evolution and the genetics underpinning contemporary human skin color diversity. “Despite the abundant genetic diversity within African populations, they have been historically underrepresented in […]

Skin Microbiome Diversity Linked to Crow’s Feet, Skin Quality

New research suggests that skin microbiome diversity may be associated with skin aging. For the study, researchers at the Center for Microbiome Innovation (CMI) at the University of California San Diego (UC San Diego) analyzed data collected during 13 studies from L’Oréal, consisting of 16S rRNA amplicon sequence data and corresponding skin clinical data for more […]

Dermavant’s Vtama Performs Well in Phase 3 AD Studies; New Data Paves Way for Upcoming sNDA Submission

Fully 80.7% of atopic dermatitis (AD) patients using Vtama (tapinarof) cream, 1% achieved Eczema Area and Severity Index (EASI ) 75 in an integrated analysis of all the ADORING Program studies, Dermavant reports. Vtama cream is a novel, aryl hydrocarbon receptor agonist in development as a once-daily, steroid-free, topical cream for both acute treatment and long-term management of AD. […]